A T-Cell Selective LNP to Deliver STING Agonists to Eliminate Autoimmune T-Cells

• RNA-based therapy that controls the cGAS-STING pathway in vivo
• cGAS-STING pathway activation in T-cells to create an intracellular factory of apoptosis-inducing signals
• Delivery of mRNA to activated T-cells mediated by targeting moieties on LNPs

Speakers:

Emily Gosselin

Director

Corner Therapeutics