Atip Lawanprasert
Postdoctoral Fellow, Murthy Lab University of California at Berkeley
Atip Lawanprasert is a postdoctoral fellow working under Prof. Niren Murthy at the Innovative Genomics Institute, UC Berkeley. His research aims to improve nucleic-acid therapeutics by developing next-generation lipid nanoparticle (LNP) delivery systems. He recently developed a high-throughput screening platform that can evaluate LNP libraries directly in challenging organs and target cells.
Atip’s background includes peptide materials, drug delivery, and nanomaterial–immune cell interactions. He earned his PhD in Bioengineering from The Pennsylvania State University, where he designed and implemented high-throughput methods for synthesizing and characterizing self-assembling biomaterials for therapeutic delivery. His work created practical biomaterial platforms, including systems for drug and vaccine delivery in demanding, non-clinical settings such as the battlefield.
Seminars
- How to optimize screening approaches to rapidly evaluate large libraries of LNP compositions and identify candidates with enhanced extrahepatic tropism?
- What screening approaches are most effective for selecting and testing targeting moieties to ensure high specificity, manufacturability, and reproducible performance after LNP conjugation?
- How can AI/ML and predictive models be integrated into experimental screening workflows to improve lipid and ligand selection?
- We develop a new high-throughput screening strategy that can screen LNP libraries and accurately predict delivery in vivo directly from tissue sequencing
- Our strategy can screen LNPs in organs that traditional screening methods are impractical, such as the heart, kidneys, and brain
- We use our strategy to screen a new class of lipids to identify LNPs with extrahepatic tropisms and low reactogenicity
