Cangjie Yang
Associate Director Zipcode Bio
Cangjie Yang is an Associate Director in Zipcode Bio, with a focus on carrier design for nucleic acid therapeutics across diverse disease indications. His current work centers on developing simplified, single-component delivery systems to enable programmable biodistribution of nucleic acids across multiple organs. Previously, he was an Associate Director at CSL Seqirus, leading lipid nanoparticle (LNP) platform development for samRNA vaccines and gene therapy programs. He has led ionizable lipid and formulation development efforts, integrating molecular design with formulation optimization and scale-up considerations to advance delivery platforms from early discovery through IND-enabling development.
Seminars
Wednesday 3rd June 2026
Engineering Single-Component Homogenous Amphiphilic Routed Particles (SHARP) to Program Organ Tropism
11:30 am
- Introduce a SHARP platform that enables efficient nucleic acid delivery without multicomponent formulation complexity
- Demonstrate programmable organ tropism achieved through molecular-level control of amphiphilic structure, enabling selective delivery to organs such as liver, lung, spleen, and the lymphatic system etc
- Highlight the translational potential and future directions of this platform for organ-selective nucleic acid therapeutics across diverse disease indications
