Jieni Xu
Head of Delivery Sciences Editas Medicine
Seminars
Thursday 4th June 2026
Roundtable Discussion: Discussing Targeted LNP Design to Minimize Immunogenicity, Maximize Safety, & Protect Sensitive Tissues for Extrahepatic Applications
2:00 pm
- How can lipid chemistry and functional group modifications be leveraged to reduce toxicity and off-target effects while maintaining delivery efficiency?
- Which design strategies and targeting ligand modifications best balance tissue specificity, immunogenicity, and safety across sensitive extrahepatic targets?
- How can LNP formulations be engineered to mitigate immune recognition and anti-drug antibody formation to achieve tolerable repeat dosing?
Thursday 4th June 2026
Chair’s Opening Remarks
8:50 am
Thursday 4th June 2026
Chair’s Closing Remarks
5:00 pm
