Stephanie Knapp
Senior Director - Delivery Sciences Mirai Bio
Seminars
Wednesday 3rd June 2026
Targeted LNPs for Immune Cell Reprogramming
3:10 pm
- Mirai’s modular targeted particle design enables rapid development of immune and blood cell targeted LNPs
- Base LNP development vi ML-based in vivo active learning dramatically reduces liver uptake
- Modular addition of targeting moieties to our base LNPs supports targeting of many hematopoietic cell types
- T cell targeted LNPs have been rapidly advanced to NHP studies with CAR cargo showing B cell depletion and high tolerability
