Engineering Single-Component Homogenous Amphiphilic Routed Particles (SHARP) to Program Organ Tropism

• Introduce a SHARP platform that enables efficient nucleic acid delivery without multicomponent formulation complexity
• Demonstrate programmable organ tropism achieved through molecular-level control of amphiphilic structure, enabling selective delivery to organs such as liver, lung, spleen, and the lymphatic system etc
• Highlight the translational potential and future directions of this platform for organ-selective nucleic acid therapeutics across diverse disease indications

Speakers:

Cangjie Yang

Associate Director

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