Bispecific Antibody-Mediated Targeting of Lipid Nanoparticles for Precision RNA Delivery
Time: 1:15 pm
day: Conference Day One
Details:
- Implementing innovative LNP targeting strategies using bispecific antibodies to confer cell specificity, enhancing RNA uptake while minimizing off-target effects, thereby optmizing therapeutic efficacy
- Validating cell-specific RNA delivery through functional assays and in vivo models, confirming the potential of bispecific antibody-guided LNPs for next-generation RNA therapeutics
- Engineering lipid nanoparticle (LNP) formulations for efficient and selective RNA delivery, achieving 100% targeting of human T cells in vitro and germinal center B cells in vivo, demonstrating precise immune cell modulation
