Phospholipids in Vaccines

Time: 3:00 pm
day: Conference Day One


  • The amphiphilic nature and safety profile of phospholipids make them ideal excipients for LNP formulations
  • The lipid composition of LNPs and their impact on the delivery of mRNA
  • Helper lipid selection can modulate the properties of LNP delivery and stability
  • DSPC with its high phase transition temperature provides excellent colloidal stability to LNPs
  • DOPE can enhance endosomal escape, while other phospholipids can target specific tissues
  • Phospholipids and their role in delivering adjuvanted liposomal vaccines