Phospholipids in Vaccines
Time: 10:30 am
day: Conference Day One
Details:
- The amphiphilic nature and safety profile of phospholipids make them ideal excipients for LNP formulations
- The lipid composition of LNPs and their impact on the delivery of mRNA
- Helper lipid selection can modulate the properties of LNP delivery and stability
- DSPC with its high phase transition temperature provides excellent colloidal stability to LNPs
- DOPE can enhance endosomal escape, while other phospholipids can target specific tissues
- Phospholipids and their role in delivering adjuvanted liposomal vaccines
