Sam Lai

Company: UNC Eshelman School of Pharmacy, University of North Carolina

Job title: Professor

Seminars:

Elucidating & Overcoming PEG-Directed Immunity Against PEGylated LNPs 12:15 pm

What is the prevalence and magnitude of pre-existing immunity against polyethylene glycol (PEG), a polymer used in vast majority of LNP formulations? Clinical evidence on LNP-induction of anti-PEG antibodies (APA), and impact on LNP medications Methods to overcome pre-existing APA and mitigate PEG-specific immunogenicity and hypersensitivityRead more

day: Conference Day Two