Development & Evaluation of a 3-component LNP With Poloxamer Coating
Time: 2:15 pm
day: Conference Day Two
Details:
- Developing a formulation of 3-component LNP coated with fast shedding off stealth polymer
- Optimizing the formulation to achieve comparable efficacy with standard LNP for in vivo expression of mAbs
- Evaluating the anti-PEG antibody and cytokine level to improve the safety and repeated dose efficacy of the novel formulation
