Jieni Xu
Company: Editas Medicine
Job title: Head of Delivery Sciences
Seminars:
Chair’s Opening Remarks 8:50 am
day: Pre-Conference Workshop Day
Development of Targeted LNP for Efficient In Vivo Editing of Hematopoietic Stem Cells 3:45 pm
Designing LNP composition to de-target from liver and redistributed to target organs of interest Developing screening platform to select targeting ligands that maximize the internalization of cell-surface targets while maintaining cellular specificity for HSCs Conjugating the improved targeting ligands on the optimal liver de-targeting base LNP achieved efficient editing of HSPCs in humanized mice as…Read more
day: Conference Day One